Test Code PTT Mx Partial Thromboplastin Time Mix
Patient Preparation
No special patient preparation required
Special Collection Instructions
Properly filled 9:1 ratio (blood to anticoagulant); 3.2% NaCitrate tube
Collection Method
Venous Draw; properly filled 9:1 ratio (blood to anticoagulant)
Minimum Volume
0.5 ml of plasma from a properly filled 1.8 mL or 2.7 mL NaCitrate (light blue) tube
Container
Light Blue Sodium Citrate
Preferred Specimen
2.7mL Lt. Blue (3.2% NaCitrate)
Acceptable Specimens
1.8 mL Lt. Blue (3.2% NaCitrate) tube
Reference or Target Ranges
Normal:
UH | 25.8 – 33.0 seconds |
WH | 26.7 – 34.3 seconds |
Reportable Units
Seconds
Critical Value
>150 Seconds
Reasons for Rejection
Hemolysis Threshold | N/A |
Icterus Threshold | N/A |
Lipemia Threshold | N/A |
Interfering Subtances/Other | Short draws, over draws, clotted, improperly labeled |
Specimen Stability
Ambient | Plasma – 4 hours – Specimens must be centrifuged within 1 hour of phlebotomy if the patient is theapeutically heparinized. |
Refrigerated (4°C to 8°C) | N/A |
Frozen(-70°C to -20°C) | 2 Weeks@ -20°C; 1 year @ -70°C |
Performance Information
Days and Time Performed | 24/7 |
Expected Turn Around Time | Routine: within 4 hours of arrival to lab |
Stat Availability | No |
Performing Bench | Coagulation |
Methodology/Method Description | UH: Stago STAR Electromagnetic mechanical clot detection system. |
Useful For
If a sample is received which has a prolonged screening test(s), (PT or PTT), and it is desired to determine whether the prolongation is the result of an anticoagulant or a factor deficiency, mixing tests should be performed. The patient sample is mixed 1:1 with commercial normal pooled plasma. The presence of 50% activity of any factor is sufficient to obtain a normal PT or PTT result. If the patient has a factor
deficiency, the normal plasma will supply enough of the missing factor to give a normal result. If the PT or PTT does not correct upon mixing, then the presence of
anticoagulant, factor inhibitors or lupus anticoagulant is possible.
CPT Codes
85732 x2