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Test Code Mumps IgG Mumps IgG

Useful For

Mumps, a paramyxovirus, causes a communicable, selflimiting disease transmitted by airborne droplets. The incubation period averages from 16 to 18 days (1). Although 30 to 40% of mumps cases remain asymptomatic, 60 to 70% have symptoms including the painful enlargement of the salivary glands and, testicular pain (males) and lower abdominal pain (females) (2, 3). Primarily a disease of children aged 4 to 15, mumps is also the most common cause of aseptic meningitis in childhood (2). Widespread use of a vaccine with attenuated mumps virus has drastically reduced the number of mumps cases, though isolated outbreaks persist. The detection of IgG antibody to mumps can be used to show immunity and detect seroconversion. The diagnosis of mumps can be made by virus isolation and identification, or by serological testing. Mumps virus can be isolated from saliva, the pharynx, or urine and, in the case of aseptic meningitis, the cerebrospinal fluid of a patient (2). Obtaining a specimen early is important since virus titer is highest initially in the course of the disease (1).

 

Sources available fromt the package insert

Preferred Specimen

Serum only

Minimum Volume

Adult: 1 mL

Pediatric: 1 mL

Specimen Stability

Serum Separated:   5 days at 2-8 °C

Container

Gold top SST Tube

Acceptable Specimen types

Serum

Days and Times Performed

Tuesday and Fridays

Collection Method

Venous Draw

Subactivity Type (Testing Location)

Special Chemistry

Instrument/Bench (Method)

Liaison DiaSorin XL 

Reference Range

Reactive

Please note: 

'Reactive' is displayed as 'normal' in the Cerner EMR

'Non-reactive' or 'equivocal' are shown as 'abnormal' in the Cerner EMR

CPT Codes

86735

Additional Test Comment

Viral IgG antibody can be formed following infection or after vaccination.  A reactive result is consistent with viral immunity. Non-reactive and equivocal results flag as abnormal which indicates non-immune or equivocal immune status.  Reactive results are posted as normal. A non-reactive result does NOT imply viral infection. If ordered in the workup of possible infection, the IgG antibody results should be interpreted in conjunction with other laboratory tests and the clinical presentation.