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HelpTest Code DHES1 Dehydroepiandrosterone Sulfate, Serum
Specimen Required
Collection Container/Tube:
Preferred: Serum gel
Acceptable: Red top
Submission Container/Tube: Plastic vial
Specimen Volume: 0.6 mL
Collection Instructions: Centrifuge and aliquot serum into a plastic vial.
Secondary ID
113595Useful For
Diagnosis and differential diagnosis of hyperandrogenism (in conjunction with measurements of other sex steroids)
An adjunct in the diagnosis of congenital adrenal hyperplasia
Diagnosis and differential diagnosis of premature adrenarche
Method Name
Immunoenzymatic Assay
Reporting Name
Dehydroepiandrosterone Sulfate, SSpecimen Type
SerumSpecimen Minimum Volume
0.5 mL
Specimen Stability Information
| Specimen Type | Temperature | Time | Special Container |
|---|---|---|---|
| Serum | Refrigerated (preferred) | 14 days | |
| Frozen | 30 days | ||
| Ambient | 7 days |
Reject Due To
| Gross hemolysis | Reject |
| Gross lipemia | OK |
| Gross icterus | OK |
Reference Values
MALES
1-14 days: DHEA-S levels in newborns are very elevated at birth but will fall to prepubertal levels within a few days.
Tanner Stages*Â
|
Mean |
Age |
Reference Range (mcg/dL) |
|
Stage I |
>14 days |
11-120 |
|
Stage II |
11.5 years |
14-323 |
|
Stage III |
13.6 years |
5.5-312 |
|
Stage IV |
15.1 years |
29-412 |
|
Stage V |
18.0 years |
104-468 |
*Puberty onset (transition from Tanner stage I to Tanner stage II) occurs for boys at a median age of 11.5 (±) 2 years. For boys, there is no proven relationship between puberty onset and body weight or ethnic origin. Progression through Tanner stages is variable. Tanner stage V (adult) is usually reached by age 18.
18-30 years: 105-728 mcg/dL
31-40 years: 57-522 mcg/dL
41-50 years: 34-395 mcg/dL
51-60 years: 20-299mcg/dL
61-70 years: 12-227 mcg/dL
≥71 years: 6.6-162 mcg/dL
FEMALES
1-14 days: DHEA-S levels in newborns are very elevated at birth but fall to prepubertal levels within a few days.
Tanner Stages*Â
|
Mean |
Age |
Reference Range (mcg/dL) |
|
Stage I |
>14 days |
16-96 |
|
Stage II |
10.5 years |
22-184 |
|
Stage III |
11.6 years |
11-296 |
|
Stage IV |
12.3 years |
17-343 |
|
Stage V |
14.5 years |
57-395 |
*Puberty onset (transition from Tanner stage I to Tanner stage II) occurs for girls at a median age of 10.5 (±) 2 years. There is evidence that it may occur up to 1 year earlier in obese girls and in African American girls. Progression through Tanner stages is variable. Tanner stage V (adult) is usually reached by age 18.
18-30 years: 83-377 mcg/dL
31-40 years: 45-295 mcg/dL
41-50 years: 27-240 mcg/dL
51-60 years: 16-195 mcg/dL
61-70 years: 9.7-159
≥71 years: 5.3-124 mcg/dL
Day(s) Performed
Monday through Friday
Report Available
1 to 3 daysPerforming Laboratory
Mayo Clinic Laboratories in Rochester
Test Classification
This test has been cleared, approved, or is exempt by the US Food and Drug Administration and is used per manufacturer's instructions. Performance characteristics were verified by Mayo Clinic in a manner consistent with CLIA requirements.CPT Code Information
82627
LOINC Code Information
| Test ID | Test Order Name | Order LOINC Value |
|---|---|---|
| DHES1 | Dehydroepiandrosterone Sulfate, S | 2191-5 |
| Result ID | Test Result Name | Result LOINC Value |
|---|---|---|
| DHES1 | Dehydroepiandrosterone Sulfate, S | 2191-5 |
Forms
If not ordering electronically, complete, print, and send a General Request (T239) with the specimen.