Test Code ANCA Cytoplasmic Neutrophil Antibodies, Serum
Reporting Name
Cytoplasmic Neutrophilic Ab, SUseful For
Evaluating patients suspected of having antineutrophil cytoplasmic antibody-associated vasculitis (granulomatosis with polyangiitis and microscopic polyangiitis, and eosinophilic granulomatosis with polyangiitis)
Performing Laboratory
![](http://d3b6ik53zt4tlx.cloudfront.net/assets/performed-by-mcl.gif)
Specimen Type
SerumAdditional Testing Requirements
When used for diagnosis, it is recommended that specific tests for proteinase 3, antineutrophil cytoplasmic antibodies (ANCA), and myeloperoxidase ANCA be performed in addition to testing for cytoplasmic ANCA and perinuclear ANCA.(1) This panel of tests is available; order VASC / Antineutrophil Cytoplasmic Antibodies Vasculitis Panel, Serum.
Specimen Required
Collection Container/Tube:
Preferred: Serum gel
Acceptable: Red top
Submission Container/Tube: Plastic vial
Specimen Volume: 0.8 mL
Collection Instructions: Centrifuge and aliquot serum into plastic vial.
Specimen Minimum Volume
0.4 mL
Specimen Stability Information
Specimen Type | Temperature | Time | Special Container |
---|---|---|---|
Serum | Refrigerated (preferred) | 21 days | |
Frozen | 21 days |
Reference Values
Negative
If positive for antineutrophil cytoplasmic antibodies, results are titered.
Day(s) Performed
Monday through Saturday
Test Classification
This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. It has not been cleared or approved by the US Food and Drug Administration.CPT Code Information
86036 x2
86037-Titer (if appropriate)
LOINC Code Information
Test ID | Test Order Name | Order LOINC Value |
---|---|---|
ANCA | Cytoplasmic Neutrophilic Ab, S | 87427-1 |
Result ID | Test Result Name | Result LOINC Value |
---|---|---|
3114 | c-ANCA | In Process |
3119 | p-ANCA | 17357-5 |
Report Available
3 to 4 daysReject Due To
Gross hemolysis | Reject |
Gross lipemia | Reject |
Gross icterus | OK |
Heat-treated specimen | Reject |
Method Name
Indirect Immunofluorescence
Forms
If not ordering electronically, complete, print, and send 1 of the following forms with the specimen:
-General Request (T239)
-Renal Diagnostics Test Request (T830)
Secondary ID
9441Testing Algorithm
For more information see First-Line Screening for Autoimmune Liver Disease Algorithm.